Abstract: Objective The aim of this study was to analyze the lung cancer screening rate and screening results of urban residents in Hefei from 2014 to 2016,and evaluate the effect on lung cancer screening.Methods A cluster sampling method was used to conduct a cancer risk factor questionnaire survey and an assessment of lung cancer risk factors among permanent residents aged 40~69 years old in seven districts of Hefei city.The chest low-dose spiral computed tomography(LDCT)examination was performed on the assessed high-risk population of lung cancer.The screening rate and detection rate of high-risk population were analyzed.The active follow-up and passive follow-up were used to count the number of confirmed lung cancers and calculate the incidence density of lung cancer.Results A total of 58 105 questionnaires and high-risk assessment of lung cancer were completed from 2014 to 2016,and 12 449 people were assessed at high-risk for lung cancer.The high risk rate of lung cancer was 21.43%.A total of 5 646 people participated LDCT screening(the screening participation rate was 45.35%),1 540 people were detected for lung nodules(the nodule detection rate was 27.28%),354 people were positive for nodules(the positive nodules was 6.27%)and 54 people were suspected of lung cancer(the detection rate of suspected lung cancer was 0.96%).The incidence density of lung cancer in high risk of lung cancer patients was 131.01 per 100 000 person-year.The incidence density of lung cancer with positive nodules in CT screeners was 1 255.36 per 100 000 person-year.The incidence density of lung cancer with negative nodules in CT screeners was 103.12 per 100 000 person-year.Conclusion LDCT can effectively find nodules and related lesions in the lung.It is necessary to further improve the screening mechanism,improve the screening rate of lung cancer in high-risk groups,and improve the screening effect on the level of cancer prevention and control.

Key words: Lung cancer, Screening, Low-dose spiral CT, Incidence density, Urban, Hefei