酸中毒在结直肠恶性肿瘤中的研究进展

doi:10.11904/j.issn.1002-3070.2022.01.014

Abstract

Abstract: Acidosis is one of the hallmarks of tumor microenvironment.It is closely related to glycolysis,tumor invasion and metastasis,and is affected by multiple molecular pathways.Previous studies on colorectal neoplastic diseases have found that activation of acidosis-related pathways is important mechanisms to increase the aggressiveness of colorectal tumor cells,and it can also significantly promote the occurrence and development of colorectal tumors.The combined application of targeted acidosis treatment and traditional treatment is expected to become a new direction for the treatment of colorectal tumors.

Key words: Colorectal tumors, Acidosis, Tumor invasion, Treatment

CLC Number:

R735.3⁺5

WANG Yang, LI Guodong, TANG Qingchao, LIU Ming. Research progress of acidosis in colorectal malignant tumors[J]. Journal of Practical Oncology, 2022, 36(1): 74-78.

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http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2022/V36/I1/74

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Research progress of acidosis in colorectal malignant tumors

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