细菌生物膜在肿瘤生物学进程及治疗应用中的研究进展

doi:10.11904/j.issn.1002-3070.2022.05.009

Abstract

Abstract: Bacterial biofilm is a microbial population formed by bacteria and extracellular polymers,which has the ability to enhance antibiotic resistance and anti-host immunity.Bacterial biofilms in the tumor microenvironment can induce inflammation-cancer transformation,promote cancer cell proliferation and metastasis,and enhance tumor drug-resistance,which affect the biological process of tumors.In addition,bacterial biofilms have also been shown to synergize with anticancer drugs to inhibit cancer cell proliferation,promote targeted colonization of anticancer drugs,and enhance host immune function.This paper reviews the research on bacterial biofilms in influencing the occurrence,development and anti-tumor treatment of malignant tumors.

Key words: Bacterial biofilms, Tumor, Infection

CLC Number:

R730.2

HUANG Yongping, LI Mengjie, SUN Yufang, XIANG Tao. Research progress of bacterial biofilms in tumor biological processes and therapeutic applications[J]. Journal of Practical Oncology, 2022, 36(5): 440-444.

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http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2022/V36/I5/440

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Research progress of bacterial biofilms in tumor biological processes and therapeutic applications

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