SOX4在消化系统恶性肿瘤中的研究进展

doi:10.11904/j.issn.1002-3070.2022.04.014

Abstract

Abstract: SOX4 is a member of the group C subfamily from the SOX family,and it may promote tumorigenesis by conferring the ability of cancer cells to survive,migrate and invasive.There are multiple lines of evidence supporting the idea that SOX4 is an important oncogene.SOX4 is overexpressed in a variety of malignancies,including a variety of digestive system tumors,which are the most common cause of death among cancer patients in developing countries.In recent years,the molecular mechanism of SOX4-induced malignant transformation and its relationship with digestive system tumors have become a focus of research and a frontier area.This article reviews the research status of SOX4 in digestive system tumors.

Key words: SOX4 gene, Digestive system tumors, Malignant tumor

CLC Number:

R735

ZHAO Zinan, WANG Guonian. Research progress of SOX4 in digestive system malignant tumors[J]. Journal of Practical Oncology, 2022, 36(4): 364-368.

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URL: http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/10.11904/j.issn.1002-3070.2022.04.014

http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2022/V36/I4/364

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Research progress of SOX4 in digestive system malignant tumors

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