PRACTICAL ONCOLOGY JOURNAL ›› 2014, Vol. 28 ›› Issue (4): 349-353.doi: 10.11904/j.issn.1002-3070.2014.04.013

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Progress on antitumor activity and its mechanisms of morinda citrifolia

CHEN Jianguo1, LI Jinxia1,2,3, CHENG Chi1   

  1. 11.China National Research Institute of Food and Fermentation Industries,Beijing 100015,China ;2China Center of Industrial Culture Collection;3Tianjin University of Science & Technology, College of Bioengineering
  • Online:2014-08-28 Published:2014-07-31

Abstract: AbstractThis paper summarizes the progress on anti-tumor effect and its mechanism of Noni over the past decade. Plenty of tests indicated that noni juice, juice extracts, leaf and root extracts have anti-tumor effects. It can inhibit tumor growth through inducing tumor cell apoptosis, activating host immune system, inhibition of angiogenesis and cyclooxygenase, anti-oxidation and blocking carcinogen -DNA adduct formation. This paper provides a reference for the adjuvant therapy of anticancer drugs and food form Noni.

Key words: noni, Morinda citrifolia Linn, Anticancer, Mechanism

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