PRACTICAL ONCOLOGY JOURNAL ›› 2017, Vol. 31 ›› Issue (1): 93-96.doi: 10.11904/j.issn.1002-3070.2017.01.020

• Review • Previous Articles    

Advances in the tumor related research of IRF-4 binding protein

HOU Yangming1, XU Yingjuan2, CUI Yunfu1   

  1. 1.Department of Biliary and Pancreatic Surgery,The Second Affiliated Hospital of Harbin Medical University,Harbin 150086,China;
    2.Department of Gynecology,The Affiliated Turmor Hospital of Harbin Medical University
  • Received:2016-09-30 Online:2017-02-28 Published:2017-02-20

Abstract: Interferon regulatory factor-4 binding protein(IBP),served as a novel type of microtubule binding protein,is proven to play an important role in the immune system.New evidence suggests that the protein is associated with the occurrence and development of some malignant tumors through the effects of cytoskeletal remodeling and cell conduction mechanism.Therefore researchers believe that IBP may become a new target for cancer molecular therapy.Based on the existing experimental data,this study aims to investigate the structure of IBP,as well as its multiple oncology effects.Furthermore,we provide the theoretical basis for IBP targeted therapy in the treatment of malignant tumors.

Key words: IBP, Structural-function, Tumor, Mechanism

CLC Number: