Journal of Practical Oncology ›› 2019, Vol. 33 ›› Issue (6): 566-569.doi: 10.11904/j.issn.1002-3070.2019.06.018

• Review • Previous Articles     Next Articles

The role of CA153 in breast cancer immunotherapy

CAO Difei, HUANG Guoqing, XUE Jiaying, WU Qiong, WANG Lei, LI Yao   

  1. Institute of Advanced Technology,Heilongjiang Academy of Sciences,Harbin 150020,China
  • Received:2019-06-13 Revised:2019-08-29 Published:2019-12-28

Abstract: Breast cancer is a common malignant tumor in women,and immunotherapy is one of the treatments with a good clinical prognosis.CA153 can activate immune response as a specific antigen in breast cancer immune response;participate in T cell activation;target binding peptide vaccine;enhance immune response;induce dendritic cell maturation,and eliminate cancer cells in vivo.Therefore,CA153 plays an important role in the immune response and treatment of breast cancer,and can be used as a new target for breast cancer immunotherapy.

Key words: CA153, Breast cancer, Immunotherapy, Target

CLC Number: