Abstract: Lung cancer is one of the most common malignant tumors,which seriously affects people's body and mental health.In most countries around the world,its morbidity and mortality rank first,so the necessary for early screening of people at high risk for lung cancer is increasing.With the promotion and application of low-dose computed tomography(LDCT)in various countries,the mortality of lung cancer has been significantly reduced,but at the same time it has also brought many problems,such as high false positives and overdiagnosis,to cause double burden of patient economics and psychology.More and more women are passively smoking,but they are not included in the screening of high-risk lung cancer groups;The screening lung cancer for the definition and standards of high-risk pupolation as well as the definition and standard of positive nodules have not yet been unified guideline release,etc.These issues are becoming increasingly prominent,and today many studies are facing the main difficulties and challenges.This article reviews the research status and progress of LDCT in lung cancer screening.

Key words: Low-dose computed tomography, Lung cancer, Screening