Journal of Practical Oncology ›› 2020, Vol. 34 ›› Issue (1): 60-63.doi: 10.11904/j.issn.1002-3070.2020.01.011

• Review • Previous Articles     Next Articles

Application progress of antiangiogenic drugs in platinum-resistant ovarian cancer

LIANG Yongqin1, ZHAO Hongwei2   

  1. 1.Shanxi Medical University,Taiyuan 030000,China;
    2.Shanxi Provincial Cancer Hospital
  • Received:2019-09-10 Revised:2019-11-25 Online:2020-02-28 Published:2020-02-20

Abstract: Chemotherapy drugs are very limited in the treatment of platinum-resistant ovarian cancer.In recent years,several trials have shown that antiangiogenic drugs can effectively improve the prognosis of patients with drug-resistant ovarian cancer.According to different mechanisms of action,antiangiogenic drugs are divided into vascular endothelial growth factor inhibitors,vascular endothelial growth factor receptor inhibitors,tyrosine kinase inhibitors and integrin inhibitors,and described the research progress of antiang iogenic drugs in the treatment of platinum-resistant ovarian cancer.

Key words: Ovarian cancer, Antiangiogenic drugs, Drug resistance

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